RESUMEN
Objective: Slowing information processing speed (IPS) is a biomarker of neuronal damage in patients with multiple sclerosis (pwMS). A focus on IPS might be the ideal solution in the perspective of promptly detecting cognitive changes over time. We developed a tablet-based home-made videogame to test the sensitivity of this device in measuring subclinical IPS in pwMS. Materials and Methods: Forty-three pwMS without cognitive impairment and 20 healthy controls (HCs) were administered the videogame task with a tablet. Response times (RTs) and accuracy were recorded. Results: PwMS (mean RTs = 505.5 ± 73.9 ms) were significantly slower than HCs (mean RTs = 462.3 ± 40.3 ms, P = 0.014) on the videogame task. A moderate but significant correlation (r = -0.35, P = 0.03) between mean RTs and the Symbol Digit Modalities Test was observed. Conclusion: Our videogame showed good sensitivity in measuring IPS in apparently cognitive normal pwMS. Computerized testing might be useful in screening initial cognitive dysfunction that should be monitored as a marker of underlying disease progression. IRB approval Number is 2332CESC.
Asunto(s)
Procesamiento Automatizado de Datos/normas , Esclerosis Múltiple/complicaciones , Juegos de Video/normas , Adulto , Procesamiento Automatizado de Datos/clasificación , Femenino , Humanos , Modelos Lineales , Masculino , Persona de Mediana Edad , Tiempo de Reacción/fisiología , Juegos de Video/tendenciasRESUMEN
BACKGROUND: Support vector machine (SVM) has been widely used as accurate and reliable method to decipher brain patterns from functional MRI (fMRI) data. Previous studies have not found a clear benefit for non-linear (polynomial kernel) SVM versus linear one. Here, a more effective non-linear SVM using radial basis function (RBF) kernel is compared with linear SVM. Different from traditional studies which focused either merely on the evaluation of different types of SVM or the voxel selection methods, we aimed to investigate the overall performance of linear and RBF SVM for fMRI classification together with voxel selection schemes on classification accuracy and time-consuming. METHODOLOGY/PRINCIPAL FINDINGS: Six different voxel selection methods were employed to decide which voxels of fMRI data would be included in SVM classifiers with linear and RBF kernels in classifying 4-category objects. Then the overall performances of voxel selection and classification methods were compared. Results showed that: (1) Voxel selection had an important impact on the classification accuracy of the classifiers: in a relative low dimensional feature space, RBF SVM outperformed linear SVM significantly; in a relative high dimensional space, linear SVM performed better than its counterpart; (2) Considering the classification accuracy and time-consuming holistically, linear SVM with relative more voxels as features and RBF SVM with small set of voxels (after PCA) could achieve the better accuracy and cost shorter time. CONCLUSIONS/SIGNIFICANCE: The present work provides the first empirical result of linear and RBF SVM in classification of fMRI data, combined with voxel selection methods. Based on the findings, if only classification accuracy was concerned, RBF SVM with appropriate small voxels and linear SVM with relative more voxels were two suggested solutions; if users concerned more about the computational time, RBF SVM with relative small set of voxels when part of the principal components were kept as features was a better choice.
Asunto(s)
Algoritmos , Procesamiento Automatizado de Datos/métodos , Imagen por Resonancia Magnética/métodos , Reconocimiento de Normas Patrones Automatizadas/métodos , Programas Informáticos , Mapeo Encefálico/clasificación , Mapeo Encefálico/métodos , Mapeo Encefálico/estadística & datos numéricos , Biología Computacional/clasificación , Biología Computacional/métodos , Biología Computacional/estadística & datos numéricos , Procesamiento Automatizado de Datos/clasificación , Femenino , Humanos , Masculino , Dinámicas no Lineales , Reconocimiento de Normas Patrones Automatizadas/clasificación , Reproducibilidad de los Resultados , Programas Informáticos/clasificaciónAsunto(s)
Procesamiento Automatizado de Datos/legislación & jurisprudencia , Health Insurance Portability and Accountability Act , Formulario de Reclamación de Seguro/legislación & jurisprudencia , Médicos/clasificación , Procesamiento Automatizado de Datos/clasificación , Control de Formularios y Registros/clasificación , Control de Formularios y Registros/legislación & jurisprudencia , Adhesión a Directriz , Humanos , Médicos/legislación & jurisprudencia , Estados UnidosRESUMEN
This article aims at showing an architecture of neural networks designed for the classification of data distributed among a high number of classes. A significant gain in the global classification rate can be obtained by using our architecture. This latter is based on a set of several little neural networks, each one discriminating only two classes. The specialization of each neural network simplifies their structure and improves the classification. Moreover, the learning step automatically determines the number of hidden neurons. The discussion is illustrated by tests on databases from the UCI machine learning database repository. The experimental results show that this architecture can achieve a faster learning, simpler neural networks and an improved performance in classification.
Asunto(s)
Sistemas de Computación , Procesamiento Automatizado de Datos/clasificación , Redes Neurales de la ComputaciónRESUMEN
Are HIM professionals ready to make the most of APCs? This article suggests some strategies to improve the way we work with APCs, focus on complete and accurate coding, and improve our expertise.
Asunto(s)
Atención Ambulatoria/clasificación , Procesamiento Automatizado de Datos/clasificación , Formulario de Reclamación de Seguro/clasificación , Servicio de Registros Médicos en Hospital/organización & administración , Sistemas de Registros Médicos Computarizados/clasificación , Medicare/organización & administración , Atención Ambulatoria/economía , Current Procedural Terminology , Grupos Diagnósticos Relacionados , Educación Continua , Eficiencia Organizacional , Procesamiento Automatizado de Datos/normas , Administración Financiera de Hospitales , Control de Formularios y Registros , Guías como Asunto , Humanos , Relaciones Interdepartamentales , Internet , Administradores de Registros Médicos/educación , Estados Unidos , Simplificación del TrabajoRESUMEN
No disponible
Asunto(s)
Anamnesis Homeopática , Informática Médica/métodos , Informática Médica/normas , Sistemas de Información/organización & administración , Sistemas de Información , Automatización/métodos , Automatización/normas , Procesamiento Automatizado de Datos/normas , Procesamiento Automatizado de Datos/métodos , Informática Médica/organización & administración , Informática Médica/tendencias , Procesamiento Automatizado de Datos/clasificación , Procesamiento Automatizado de Datos/instrumentación , Procesamiento Automatizado de Datos/tendenciasAsunto(s)
Grupos Diagnósticos Relacionados/clasificación , Procesamiento Automatizado de Datos/clasificación , Servicio de Registros Médicos en Hospital/organización & administración , Registros Médicos/clasificación , Rol del Médico , Indización y Redacción de Resúmenes , Hospitales con 100 a 299 Camas , Relaciones Médico-Hospital , OklahomaRESUMEN
This rule proposes a standard for a national employer identifier and requirements concerning its use by health plans, health care clearinghouses, and health care providers. The health plans, health care clearinghouses, and health care providers would use the identifier, among other uses, in connection with certain electronic transactions. The use of this identifier would improve the Medicare and Medicaid programs, and other Federal health programs and private health programs, and the effectiveness and efficiency of the health care industry in general, by simplifying the administration of the system and enabling the efficient electronic transmission of certain health information. It would implement some of the requirements of the Administrative Simplification subtitle of the Health Insurance Portability and Accountability Act of 1996.
Asunto(s)
Procesamiento Automatizado de Datos/clasificación , Formulario de Reclamación de Seguro/clasificación , Medicaid/organización & administración , Medicare/organización & administración , Movilidad Laboral , Centers for Medicare and Medicaid Services, U.S. , Planes de Asistencia Médica para Empleados/clasificación , Aseguradoras , Estados Unidos , Simplificación del TrabajoRESUMEN
This rule proposes a standard for a national health care provider identifier and requirements concerning its use by health plans, health care clearinghouses, and health care providers. The health plans, health care clearinghouses, and health care providers would use the identifier, among other uses, in connection with certain electronic transactions. The use of this identifier would improve the Medicare and Medicaid programs, and other Federal health programs and private health programs, and the effectiveness and efficiency of the health care industry in general, by simplifying the administration of the system and enabling the efficient electronic transmission of certain health information. It would implement some of the requirements of the Administrative Simplification subtitle of the Health Insurance Portability and Accountability Act of 1996.
Asunto(s)
Procesamiento Automatizado de Datos/normas , Instituciones de Salud/clasificación , Personal de Salud/clasificación , Formulario de Reclamación de Seguro/normas , Asistencia Médica/organización & administración , Centers for Medicare and Medicaid Services, U.S. , Procesamiento Automatizado de Datos/clasificación , Control de Formularios y Registros , Formulario de Reclamación de Seguro/clasificación , Medicaid/legislación & jurisprudencia , Medicaid/organización & administración , Asistencia Médica/legislación & jurisprudencia , Medicare/legislación & jurisprudencia , Medicare/organización & administración , Estados UnidosAsunto(s)
Procesamiento Automatizado de Datos/clasificación , Equipos y Suministros de Hospitales/clasificación , Administración de Materiales de Hospital/métodos , Análisis Costo-Beneficio , Toma de Decisiones en la Organización , Equipos y Suministros de Hospitales/provisión & distribución , Sistemas de Información Administrativa , Proyectos Piloto , Estados UnidosAsunto(s)
Procesamiento Automatizado de Datos/normas , Inventarios de Hospitales/normas , Administración de Materiales de Hospital/organización & administración , Redes de Comunicación de Computadores , Servicios Contratados , Procesamiento Automatizado de Datos/clasificación , Adquisición en Grupo , Hospitales Militares , Inventarios de Hospitales/clasificación , Administración de Materiales de Hospital/clasificación , Estados UnidosAsunto(s)
Sistemas de Registros Médicos Computarizados/normas , Indización y Redacción de Resúmenes/normas , Indización y Redacción de Resúmenes/tendencias , Procesamiento Automatizado de Datos/clasificación , Control de Formularios y Registros , Sistemas de Registros Médicos Computarizados/clasificación , Estándares de Referencia , Unified Medical Language System , Estados UnidosRESUMEN
British Columbia (B.C.) provides an excellent opportunity to study the accuracy of assigning Underlying Cause of Death (UCOD) in Down syndrome. The study was designed to evaluate the effect of inappropriate interpretation of guidelines for completing the death certificate. All B.C. livebirths identified as having Down syndrome during the period 1952-1981 were collected from the records of the B.C. Health Surveillance Registry. Of the 1,337 affected individuals identified, 324 (24.2%) had died. The death certificates on these individuals were reviewed to assess from the information on the death certificate whether the underlying cause of death appeared to have been assigned in accordance to World Health Organization coding guidelines. The UCOD appeared to be assigned appropriately for 165/315 cases (52.4%). It is possible that in the situation where an easily recognizable condition such as Down syndrome is present, the need to identify the actual UCOD may be viewed as less urgent compared with cases where an apparently "normal" individual dies.